Alzheimer's Drug Reverses Cognitive Decline Over 12 Month Period In Early Human Testing

A drug once approved as an antihistamine in Russia improved thinking processes and ability to function in patients with Alzheimer's disease in a study conducted there, said an expert at Baylor College of Medicine in Houston. The findings are published in the journal The Lancet. "More research is needed, but we are encouraged by the effect the drug Dimebon had on Alzheimer's patients" said Dr. Rachelle Doody, professor of neurology at BCM and lead author of the study. In the study, the authors noted that Dimebon is the first drug for Alzheimer's disease that demonstrated continued improvement in patients over a 12 month period. Other approved drugs do not have this effect. Half of the 183 patients in the Russian study received Dimebon; the other half were given a placebo or an inactive pill. Clinicians at the study sites then monitored the patients' progress over the next year on five different outcomes. All of those in the study had mild to moderate Alzheimer's disease. "What we saw in the clinical trial is that people on the medication continued to improve over time," Doody said. "Those on placebo continued to decline."Researchers believe the medication works by stabilizing mitochondria, the cellular components that produce energy, and possibly by inhibiting brain cell death. Researchers evaluated patients' thinking and memory ability, overall function, psychiatric and behavioral symptoms, and ability to perform daily activities.

"Usually at this point in a drug's development, we are happy to see improvement in one of the outcome measures," Doody said. "We saw improvement in all five."
Some participants complained of occasional dry mouth, but no one opted out of the study because of the side effects.
"As we continue research, we hope to replicate these results," Doody said. "My belief is that this drug will turn out to be useful for Alzheimer's disease, regardless of the stage of the disease."

Volcanic Eruptions May Have Wiped Out Ocean Life 94 Million Years Ago

Undersea volcanic activity triggered a mass extinction of marine life and buried a thick mat of organic matter on the sea floor about 93 million years ago, which became a major source of oil, according to a new study. "It certainly caused an extinction of several species in the marine environment," said University of Alberta Earth and Atmospheric Science researcher Steven Turgeon. "It wasn't as big as what killed off the dinosaurs, but it was what we call an extreme event in the Earth's history, something that doesn't happen very often." "Of the big five mass extinctions in the Earth's history, most of them were some kind of impact with the planet's surface," said Turgeon. "This one is completely Earth-bound, it's strictly a natural phenomenon."

Hydrogen Vehicles Coming Soon? Two Million Could Be On Roads By 2020

A transition to hydrogen vehicles could greatly reduce U.S. oil dependence and carbon dioxide emissions, says a new congressionally mandated report from the National Research Council, but making hydrogen vehicles competitive in the automotive market will not be easy. While the development of fuel cell and hydrogen production technology over the past several years has been impressive, challenges remain. Vehicle costs are high, and the U.S. currently lacks the infrastructure to produce and widely distribute hydrogen to consumers. These obstacles could be overcome, however, with continued support for research and development and firm commitments from the automotive industry and the federal government, concluded the committee that wrote the report. Light-duty vehicles, such as cars, SUVs, and pickup trucks, are responsible for 44 percent of the oil used in the United States and over 20 percent of the carbon dioxide emitted. Concerns over climate change, oil imports, and recent spikes in gasoline prices have spurred interest in the development of alternative fuels. In 2003, President Bush announced a $1.2 billion initiative to encourage development of hydrogen production technology and fuel cell vehicles, which are powered through a chemical reaction between hydrogen and oxygen and emit only water and heat as exhaust. The committee estimated the maximum number of hydrogen vehicles that could be on the road in the coming decades, assuming that practical technical goals are met, that consumers want hydrogen cars, and that government policies are in place to help drive the transition from oil to hydrogen fuel. The findings therefore represent potential best-case scenarios rather than predictions.

Bees Go 'Off-color' When They Are Sickly

Bumble-bees go 'off colour' and can't remember which flowers have the most nectar when they are feeling under the weather, a new study from the University of Leicester reveals. The behaviour of the bumbling bees reveals that, like humans who are ill, bees are often not at their most astute and clever when they feel poorly.

Lecturer in Animal Biology at the University of Leicester Dr. Eamonn Mallon, who lead the research group, said: "Disease can influence different behaviours including foraging, mate choice, and predator avoidance. Several recent papers have shown reduced learning abilities in infected insects. However, it is difficult to separate the effects of the immune response from the direct effects of the parasite. That was the purpose of our study"
Bees were divided into a control group and a group that were injected with lipopolysaccharide, a substance that stimulated an immune response without a need for the bee to be infected with a disease. Bees were offered the choice of blue and yellow artificial flowers only one type of which contained sugar water. An individual's flight was recorded over ninety visits to these flowers. Eventually the bees spent almost all of their time going to the rewarding flowers, but it took the immune stimulated bees longer to reach this point.

Insect Warning Colors Aid Cancer And Tropical Disease Drug Discovery

Brightly colored beetles or butterfly larvae nibbling on a plant may signal the presence of chemical compounds active against cancer cell lines and tropical parasitic diseases, according to researchers at Smithsonian's Tropical Research Institute in Panama. Such clues could speed drug discovery and provide insight into the ecological relationships between tropical-forest plants and insects that feed on them. "These findings are incredibly exciting and important," said Todd Capson, STRI research chemist, who directed the project. "The results of this study could have direct and positive impacts on the future of medical treatment for many diseases around the world."

Scientists Learn How Food Affects The Brain: Omega 3 Especially Important

In addition to helping protect us from heart disease and cancer, a balanced diet and regular exercise can also protect the brain and ward off mental disorders. "Food is like a pharmaceutical compound that affects the brain," said Fernando Gómez-Pinilla, a UCLA professor of neurosurgery and physiological science who has spent years studying the effects of food, exercise and sleep on the brain. "Diet, exercise and sleep have the potential to alter our brain health and mental function. This raises the exciting possibility that changes in diet are a viable strategy for enhancing cognitive abilities, protecting the brain from damage and counteracting the effects of aging." Omega-3 fatty acids -- found in salmon, walnuts and kiwi fruit -- provide many benefits, including improving learning and memory and helping to fight against such mental disorders as depression and mood disorders, schizophrenia, and dementia, said Gómez-Pinilla, a member of UCLA's Brain Research Institute and Brain Injury Research Center. "Omega-3 fatty acids support synaptic plasticity and seem to positively affect the expression of several molecules related to learning and memory that are found on synapses," Gómez-Pinilla said. "Omega-3 fatty acids are essential for normal brain function. "Dietary deficiency of omega-3 fatty acids in humans has been associated with increased risk of several mental disorders, including attention-deficit disorder, dyslexia, dementia, depression, bipolar disorder and schizophrenia," he said. "A deficiency of omega-3 fatty acids in rodents results in impaired learning and memory." Children who had increased amounts of omega-3 fatty acids performed better in school, in reading and in spelling and had fewer behavioral problems, he said.

Children Are Naturally Prone To Be Empathic And Moral

Children between the ages of seven and 12 appear to be naturally inclined to feel empathy for others in pain, according to researchers at the University of Chicago, who used functional Magnetic Resonance Imaging (fMRI) scans to study responses in children. The responses on the scans were similar to those found in studies of adults. Researchers found that children, like adults, show responses to pain in the same areas of their brains. The research also found additional aspects of the brain activated in children, when youngsters saw another person intentionally hurt by another individual."This study is the first to examine in young children both the neural response to pain in others and the impact of someone causing pain to someone else," said Jean Decety, Professor in the Departments of Psychology and Psychiatry at the University of Chicago. The programming for empathy is something that is "hard-wired" into the brains of normal children, and not entirely the product of parental guidance or other nurturing, said Decety. Understanding the brain's role in responding to pain can help researchers understand how brain impairments influence anti-social behavior, such as bullying, he explained.

Brain Cells Related To Fear Identified

he National Institute of Mental Health estimates that in any given year, about 40 million adults (18 or older) will suffer from some form of anxiety disorder, including debilitating conditions such as phobias, panic disorders and post-traumatic stress disorder (PTSD). It is estimated that nearly 15 percent of U.S. soldiers returning from Iraq and Afghanistan develop PTSD, underscoring the urgency to develop better treatment strategies for anxiety disorders. These disorders can lead to myriad problems that hinder daily life – or ruin it altogether – such as drug abuse, alcoholism, marital problems, unemployment and suicide. Functional imaging studies in combat veterans have revealed that the amygdala, a cerebral structure of the temporal lobe known to play a key role in fear and anxiety, is hyperactive in PTSD subjects. Potentially paving the way for more effective treatments of anxiety disorders, a recent Nature report by Denis Paré, professor at the Center for Molecular and Behavioral Neuroscience at Rutgers University in Newark, has identified a critical component of the amygdala’s neural network normally involved in the extinction, or elimination, of fear memories. Paré’s laboratory studies the amygdala and how its activity impacts behavior. His research was published online by Nature on July 9, 2008 and is scheduled to appear in the print edition later in July. Earlier research has revealed that in animals and humans, the amygdala is involved in the expression of innate fear responses, such as the fear of snakes, along with the formation of new fear memories as a result of experience, such as learning to fear the sound of a siren that predicts an air raid.

Art Therapy Useful To Treat Mental Disease

Elizaberta López Pérez, a Bachelor of Fine Arts and doctor in Painting at the University of Granada, has carried out one of the first studies in a Spanish university on the use of art therapy for the treatment of acute mental sick persons. Her work, based on psychoanalysis principles, starts from a basic premise: A work of art is a sign formed as a vital trace and its essential material is the humanity of the human being who leaves his memory in the world. Art therapy or therapy through art, a current started in the middle of the 20th century, uses visual arts with therapeutic purposes. It is based on the idea that visual representations, objectified through plastic material, contribute to the construction of a meaning of the psychic conflicts, and favour its resolution. Plastic representation would be, from this point of view, a process for thought construction.

Rare 'Star-Making Machine' Found In Distant Universe

Astronomers have uncovered an extreme stellar machine -- a galaxy in the very remote universe pumping out stars at a surprising rate of up to 4,000 per year. In comparison, our own Milky Way galaxy turns out an average of just 10 stars per year. The discovery, made possible by several telescopes including NASA's Spitzer Space Telescope, goes against the most common theory of galaxy formation. According to the theory, called the Hierarchical Model, galaxies slowly bulk up their stars over time by absorbing tiny pieces of galaxies -- and not in one big burst as observed in the newfound "Baby Boom" galaxy. "This galaxy is undergoing a major baby boom, producing most of its stars all at once," said Peter Capak of NASA's Spitzer Science Center at the California Institute of Technology, Pasadena. "If our human population was produced in a similar boom, then almost all of the people alive today would be the same age." Capak is lead author of a new report detailing the discovery in the July 10th issue of Astrophysical Journal Letters.

One-third Of Reef-building Corals Face Extinction

One third of reef-building corals around the world are threatened with extinction, according to the first-ever comprehensive global assessment to determine their conservation status. The study findings were published today by Science Express. Leading coral experts joined forces with the Global Marine Species Assessment (GMSA) -- a joint initiative of the International Union for Conservation of Nature (IUCN) and Conservation International (CI) -- to apply the IUCN Red List Categories and Criteria to this important group of marine species. "The results of this study are very disconcerting," stated Kent Carpenter, lead author of the Science article, GMSA Director, IUCN Species Programme. "When corals die off, so do the other plants and animals that depend on coral reefs for food and shelter, and this can lead to the collapse of entire ecosystems."

New 'Window' Opens On Solar Energy: Cost Effective Devices Available Soon

Imagine windows that not only provide a clear view and illuminate rooms, but also use sunlight to efficiently help power the building they are part of. MIT engineers report a new approach to harnessing the sun's energy that could allow just that. The work, reported in the July 11 issue of Science, involves the creation of a novel "solar concentrator." "Light is collected over a large area [like a window] and gathered, or concentrated, at the edges," explains Marc A. Baldo, leader of the work and the Esther and Harold E. Edgerton Career Development Associate Professor of Electrical Engineering. As a result, rather than covering a roof with expensive solar cells (the semiconductor devices that transform sunlight into electricity), the cells only need to be around the edges of a flat glass panel. In addition, the focused light increases the electrical power obtained from each solar cell "by a factor of over 40," Baldo says.

Super Computer for Molecular Mysteries

A privately financed team of scientists and engineers is nearing completion of a special-purpose supercomputer intended to offer more than a thousandfold increase in performance for complex molecular simulations. The machine, named Anton, in homage to Anton van Leeuwenhoek, a pioneer in microbiology, is a bold gamble to jump ahead of the most powerful general-purpose supercomputers by as much as a half decade. It could be used to investigate problems of great scientific interest, like the folding of protein molecules, and in the design of drugs based on the simulated biological activity of different molecules. Anton is massively parallel, with 512 specialized processors working simultaneously. The processors are called application-specific integrated circuits, and in this case their specialty is the calculation of the three-dimensional characteristics of molecules. Despite the publication of a detailed technical description of his computer, Mr. Shaw declined to be interviewed about the project. “At this stage of our research, though, we’ve been trying to communicate our results largely through academic talks and peer-reviewed publications in scientific journals,” he wrote in an e-mail message. Experimentation in the use of supercomputers to model molecular interactions has been going on for more than a decade, but the field is still largely in its infancy. Simulations of processes like the folding of proteins into three-dimensional structures or the interactions between proteins or between a protein and a drug molecule hold out the promise of advancing science and drug development.

First DNA Molecule Made Almost Entirely Of Artificial Parts

Chemists in Japan report development of the world's first DNA molecule made almost entirely of artificial parts. The finding could lead to improvements in gene therapy, futuristic nano-sized computers, and other high-tech advances, they say. In the new study, Masahiko Inouye and colleagues point out that scientists have tried for years to develop artificial versions of DNA in order to extend its amazing information storage capabilities. The researchers used high-tech DNA synthesis equipment to stitch together four entirely new, artificial bases inside the sugar-based framework of a DNA molecule. This resulted in unusually stable, double-stranded structures resembling natural DNA. Like natural DNA, the new structures were right-handed and some easily formed triple-stranded structures. The unique chemistry of these structures and their high stability offer unprecedented possibilities for developing new biotech materials and applications, the researchers say.

Music Went With Cave Art In Prehistoric Caves

Thousands of years later, we can view stone-age art on cave walls, but we can't listen to the stone-age music that would have accompanied many of the pictures. In many sites, flutes made of bone are to be found nearby. Iegor Reznikoff of the University of Paris reports that the most acoustically resonant place in a cave -- where sounds linger or reverberate the most -- was also often the place where the pictures were densest. And when the most-resonant spot was located in a very narrow passageway too difficult for painting, red marks are often found, as if the resonance maximum had to be signified in some way. This correlation of paintings and music, Reznikoff says, provides "the best evidence for the ritualistic meanings of the paintings and of the use of the adorned caves." Proceeding into the direction of the best resonance (or echo) that answers to vocal sounds, one is naturally lead to panels with pictures. At the very least, in the dark caves, where hand-held light sources fall off in effectiveness, singing (and listening for resonant reactions) proved to be the best sonar-like way of exploring the caves. A significant returning sound gave some hint of a usable hall ahead in the dark.

Mining For Molecules In The Milky Way

Scientists are using the giant Robert C. Byrd Green Bank Telescope (GBT) to go prospecting in a rich molecular cloud in our Milky Way Galaxy. They seek to discover new, complex molecules in interstellar space that may be precursors to life. "Clouds like this one are the raw material for new stars and planets. We know that complex chemistry builds prebiotic molecules in such clouds long before the stars and planets are formed. There is a good chance that some of these interstellar molecules may find their way to the surface of young planets such as the early Earth, and provide a head start for the chemistry of life. For the first time, we now have the capability to make a very thorough and methodical search to find all the chemicals in the clouds," said Anthony Remijan, of the National Radio Astronomy Observatory (NRAO).

Scientists Identify the Brain’s Activity Hub

The outer layer of the brain, the reasoning, planning and self-aware region known as the cerebral cortex, has a central clearinghouse of activity below the crown of the head that is widely connected to more-specialized regions in a large network similar to a subway map, scientists reported Monday. The new report, published in the free-access online journal PLoS Biology, provides the most complete rough draft to date of the cortex’s electrical architecture, the cluster of interconnected nodes and hubs that help guide thinking and behavior. The paper also provides a striking demonstration of how new imaging techniques focused on the brain’s white matter — the connections between cells, rather than the neurons themselves — are filling in a dimension of human brain function that has been all but dark. In previous studies, scientists have used magnetic resonance imaging to identify peaks and valleys of neural activity when people are doing various things, like making decisions, reacting to frightening images or reliving painful memories. But these studies, while provocative, revealed virtually nothing about the underlying neural networks involved — about which brain regions speak to one another and when. Previous estimates of network structure, based on such imaging, have been sketchy.The new findings, while not conclusive, give scientists what is essentially a wiring diagram that they can test and refine. Dr. Sporns said continued research should help produce a complete and detailed neural wiring diagram, what he called the “connectome” of the brain. “We hope we can get to a place where we have, in effect, a brain simulator, in the same way we have computer models that can simulate the climate,” he said, “so we can simulate activation patterns we see in clinical cases,” like psychiatric problems and brain injuries.

Deep Down, We Can’t Fool Even Ourselves

In voting against the Bush tax cut in 2001, Senator John McCain said he “cannot in good conscience support a tax cut in which so many of the benefits go to the most fortunate.” Today he campaigns in favor of extending that same tax cut beyond its expiration date. Senator Barack Obama last year called himself a “longtime advocate” of public financing of election campaigns. This month, he reiterated his “support” for such financing while becoming the first major party presidential nominee ever to reject it for his own campaign.Do you think either of these men is a hypocrite?If so, does this hypocrite really believe, in his heart, what he is saying? Fortunately, we don’t need to get into the fine points of taxes or campaign finances to take a stab at these questions. We can probably get further by looking at some experiments in what psychologists call moral hypocrisy. This is a more devious form of hypocrisy than what was exhibited by, say, the governor of New York when he got caught patronizing a prostitute. It was obviously hypocritical behavior for a public official who had formerly prosecuted prostitutes and increased penalties for their customers, but at least Eliot Spitzer acknowledged his actions were wrong by anyone’s standards. The moral hypocrite, by contrast, has convinced himself that he is acting virtuously even when he does something he would condemn in others. You can understand this “self-halo” effect — and perhaps discover it in someone very close to you— by considering what happened when two psychologists, Piercarlo Valdesolo and David DeSteno, tested people’s reactions to the following situation.

You show up for an experiment and are told that you and a person arriving later will each have to do a different task on a computer. One job involves a fairly easy hunt through photos that will take just 10 minutes. The other task is a more tedious exercise in mental geometry that takes 45 minutes.

You get to decide how to divvy up the chores: either let a computer assign the tasks randomly, or make the assignments yourself. Either way, the other person will not know you had anything to do with the assignments.

Now, what is the fair way to divvy up the chores?

When the researchers posed this question in the abstract to people who were not involved in the tasks, everyone gave the same answer: It would be unfair to give yourself the easy job.
But when the researchers actually put another group of people in this situation, more than three-quarters of them took the easy job. Then, under subsequent questioning, they gave themselves high marks for acting fairly. The researchers call this moral hypocrisy because the people were absolving themselves of violating a widely held standard of fairness (even though they themselves hadn’t explicitly endorsed that standard beforehand).
The more interesting question is how presidential candidates, and their supporters, turn into hypocrites. It has been demonstrated repeatedly in experiments that humans are remarkably sensitive to unfairness. We’ve survived as social animals because we are so good at spotting selfishness and punishing antisocial behavior.
So how we do violate our own moral code? Does our gut instinct for self-preservation override our moral reasoning? Do we use our powers of rationality to override our moral instinct?
“The question here,” Dr. DeSteno said, “is whether we’re designed at heart to be fair or selfish.”

Numerology

My cousin, bound for a top liberal arts college in the fall, was amused when I told her I was reviewing a book about big ideas in mathematics, from the classical to the contemporary. “Don’t they already know everything about math?” she asked. “You know, there’s algebra ... and then calculus ... and that’s it, right?”

Andrew Hodges, a fellow at Oxford and the author of the lively new book “One to Nine,” would have been horrified, but not surprised. My cousin, in his view, is a victim of the pedagogical tradition that presents math as an eternally fixed array of computations, to be memorized and repeatedly executed without motivation or explanation. The result, he writes, is a “legacy of fear and anxiety generated by schools, which leaves most of their victims with a lifetime of mumbling apologetically about ‘my worst subject.’”
“One to Nine” offers a different model for teaching math — discursive rather than linear, topical rather than abstract and remote, and, above all, manically energetic rather than repetitive and plodding. The book is composed of nine chapters, each focused — very, very softly focused — on one of the first nine natural numbers. Chapter Four, for instance, starts out with the observation that four is a perfect square, and from there skips along to the construction of Latin squares, the irrationality of the square root of two, the definition of the logarithm (whose relation to “four” never comes entirely clear), complex numbers, and the even more exotic quaternions (a number system in which “numbers” are actually strings of four integers, and the product of two numbers depends on the order in which you multiply them!), the theory of four-dimensional spacetime and Einstein’s equation E=mc2 (squares again) before finishing with a short and speculative account of the theory of twistors, one of many competing candidates for the universe’s underlying geometry. NYTimes-

The Urge to End It

“There is but one truly serious philosophical problem,” Albert Camus wrote, “and that is suicide.” How to explain why, among the only species capable of pondering its own demise, whose desperate attempts to forestall mortality have spawned both armies and branches of medicine in a perpetual search for the Fountain of Youth, there are those who, by their own hand, would choose death over life? Our contradictory reactions to the act speak to the conflicted hold it has on our imaginations: revulsion mixed with fascination, scorn leavened with pity. It is a cardinal sin — but change the packaging a little, and suicide assumes the guise of heroism or high passion, the stuff of literature and art. Beyond the philosophical paradox are the bewilderingly complex dynamics of the act itself. While a universal phenomenon, the incidence of suicide varies so immensely across different population groups — among nations and cultures, ages and gender, race and religion — that any overarching theory about its root cause is rendered useless. Even identifying those subgroups that are particularly suicide-prone is of very limited help in addressing the issue. In the United States, for example, both elderly men living in Western states and white male adolescents from divorced families are at elevated risk, but since the overwhelming majority in both these groups never attempt suicide, how can we identify the truly at risk among them?.............

Long but interesting article....... http://www.nytimes.com/2008/07/06/magazine/06suicide-t.html?ref=science

Keeping an eye out for global killers

THE Earth is pockmarked with the evidence of ancient collisions — huge craters blasted into its surface by asteroids or comets. One such object, striking 65 million years ago in the Yucatán in Mexico, is believed by some experts to be linked to the demise of the dinosaurs. For a decade, NASA has been busy trying to identify what else is headed this way, particularly those potential “civilization killers” of 1 kilometer (.62 miles) or more in diameter that have orbits coming within 30 million miles of the Earth’s — too close for comfort by space standards. But the big ones are, in many ways, the easy part. Smaller rocks matter, too. Perhaps nowhere is that so evident as in central Siberia, where 100 years ago last week, something — presumably a meteoroid, most experts say — streaked across the sky and exploded at an estimated height of 28,000 feet with a force equivalent to 185 Hiroshima bombs, leveling some 800 square miles of forest. Simulations by the Sandia National Laboratories showed that object could have been just 90 feet across. NASA’s Jet Propulsion Laboratory in Pasadena, Calif., has estimated that a Tunguska-size asteroid will enter Earth’s atmosphere once every 300 years and says there may be 375,000 objects of such size out there.Fortunately, the odds are good that the next one will fall over one of our oceans, which take up more than two-thirds of the Earth’s surface, or the planet’s still-vast stretches of uninhabited lands. How much in taxpayer dollars should be invested to pinpoint such hazards is one of the toughest risk-management exercises around. “In fact, there was a daylight fireball event widely observed near Los Angeles two days ago,” Dr. Yeomans said in an e-mail message last Thursday. “I take these events as Mother Nature’s little reminders that we need to pay attention, find and track the large ones and then deflect the very few that threaten us. Tunguska was another reminder. Until recently, we humans did not pay heed to these shots across the bow but now, I think, there is more of a recognition of this low probability — but high consequence — type of event.”

Ancient Tablet Ignites Debate on Messiah and Resurrection

JERUSALEM — A three-foot-tall tablet with 87 lines of Hebrew that scholars believe dates from the decades just before the birth of Jesus is causing a quiet stir in biblical and archaeological circles, especially because it may speak of a messiah who will rise from the dead after three days. If such a messianic description really is there, it will contribute to a developing re-evaluation of both popular and scholarly views of Jesus, since it suggests that the story of his death and resurrection was not unique but part of a recognized Jewish tradition at the time. The tablet, probably found near the Dead Sea in Jordan according to some scholars who have studied it, is a rare example of a stone with ink writings from that era — in essence, a Dead Sea Scroll on stone. Still, its authenticity has so far faced no challenge, so its role in helping to understand the roots of Christianity in the devastating political crisis faced by the Jews of the time seems likely to increase. “This should shake our basic view of Christianity,” he said as he sat in his office of the Shalom Hartman Institute in Jerusalem where he is a senior fellow in addition to being the Yehezkel Kaufman Professor of Biblical Studies at Hebrew University. “Resurrection after three days becomes a motif developed before Jesus, which runs contrary to nearly all scholarship. What happens in the New Testament was adopted by Jesus and his followers based on an earlier messiah story.”

What It's Like To Be A Bat: Vocal Sonar Does More Than Locate Objects; It Cues Memory And Assists Flight

Not many people think about what it's like to be a bat, but for those who do, it's enlightening and potentially groundbreaking for understanding aspects of the human brain and nervous system. "For decades it's been recognized that a bat's voice produces sounds that give the bat information about the location of objects," says Moss. "We're now recognizing that every time a bat produces a sound there are changes in brain activity that may be important for scene analysis, sensorimotor control and spatial memory and navigation." The research could help neurobiologists understand mechanisms in the human brain and ultimately benefit human health, but that may not happen for some time as more research is needed.Moss and her colleague, Nachum Ulanovsky from the Weizmann Institute of Science in Israel, reviewed more than 100 studies and determined the brief calls emitted through a bat's mouth or nostrils and their returning echoes play a pivotal role in motor control and have other behavioral implications.In short, echoes from a bat's voice cause the bat to turn its head and ears, and give the bat's brain a description of the scene. The echoes also cue a bat's memory about its environment so it can safely fly between points. "Our review highlights new research findings suggesting that the bat's vocal production does more than yield echoes," says Moss. "We're learning every time the bat produces a vocalization, there are changes in brain activity that are essential to complex behaviors." For example, when a bat pursues prey, a moth or some other insect, it computes the 3D location of objects in its environment--a tree, a wall or a lamppost--from information carried by the echoes of high-pitched vocal chirps produced at rates of 2-150 chirps per second.Research shows it actually uses these echoes to remember details of the environment in which it operates, displaying a very sensitive spatial memory component.
According to Moss, bats engage in vocal-motor behaviors to generate signals to probe the environment, while some blind humans produce tongue clicks to generate sounds for echolocation. "All of these motor behaviors influence the animal's perception and representation of the environment," says Moss. "But of interest to us is the idea that these vocal-motor behaviors contribute to environmental perception, memory, and spatial planning far beyond the processing of sound."

"It may be that some of the information we learn from the bat gives us a window into understanding mechanisms of the human brain," says Moss. "But those outcomes are a little bit down the road."

Quantum Computing Breakthrough

An international team has identified a new hybrid atom that could be used to develop quantum computers. This data visualization shows an electron density map of the material. The funnel- or vortex-shaped figure in the lower left is an arsenic atom, and the saucer-shaped image in the center is a map of an electron binding to various atoms (each dot represents one location). The yellow dots in the upper left-center are the electron in the quantum state.

The odd behavior of a molecule in an experimental silicon computer chip has led to a discovery that opens the door to quantum computing in semiconductors. in a Nature Physics journal paper currently online, the researchers describe how they have created a new, hybrid molecule in which its quantum state can be intentionally manipulated - a required step in the building of quantum computers."Up to now large-scale quantum computing has been a dream," says Gerhard Klimeck, professor of electrical and computer engineering at Purdue University and associate director for technology for the national Network for Computational Nanotechnology."This development may not bring us a quantum computer 10 years faster, but our dreams about these machines are now more realistic." The workings of traditional computers haven't changed since they were room-sized behemoths 50 years ago; they still use bits of information, 1s and 0s, to store and process information. Quantum computers would harness the strange behaviors found in quantum physics to create computers that would carry information using quantum bits, or qubits. Computers would be able to process exponentially more information.If a traditional computer were given the task of looking up a person's phone number in a telephone book, it would look at each name in order until it found the right number. Computers can do this much faster than people, but it is still a sequential task. A quantum computer, however, could look at all of the names in the telephone book simultaneously. Albert Einstein, in a letter to Erwin Schrödinger in the 1930s, wrote that in a quantum state a keg of gunpowder would have both exploded and unexploded molecules within it (a notion that led Schrödinger to create his famous cat-in-a-box thought experiment).This "neither here nor there" quantum state is what can be controlled in this new molecule simply by altering the voltage of the transistor. Until now, the challenge had been to create a computer semiconductor in which the quantum state could be controlled, creating a qubit. "Our experiment made us realize that industrial electronic devices have now reached the level where we can study and manipulate the state of a single atom," Rogge says. "This is the ultimate limit, you can not get smaller than that."

Morbid Thoughts IncreaseThe Appetite

Can watching TV news or crime shows trigger overeating? According to new research in the Journal of Consumer Research, people who are thinking about their own deaths want to consume more. Authors Naomi Mandel (Arizona State University) and Dirk Smeesters (Erasmus University Rotterdam, the Netherlands) conducted several experiments in Europe and the United States where participants wrote essays on their feelings about their own deaths. They then checked off items on a grocery list or ate cookies. Consumers who wrote about their own deaths wanted to buy more and ate more than those who wrote about a painful medical procedure (the control group). "People want to consumer more of all kinds of foods, both healthy and unhealthy, when thinking about the idea that they will die some day," write the authors.

The researchers found people with low self-esteem, in particular, tend to over-consume after death-related thoughts. Mandel and Smeesters explain the effect using a theory called "escape from self-awareness." "When people are reminded of their inevitable mortality, they may start to feel uncomfortable about what they have done with their lives and whether they have made a significant mark on the universe. This is a state called 'heightened self-awareness.' One way to deal with such an uncomfortable state is to escape from it, by either overeating or overspending," they write.
The study also revealed that placing a mirror in front of the participants reduced the desire to over-consume.
"Consumers, especially those with a lower self-esteem, might be more susceptible to over-consumption when faced with images of death during the news or their favorite crime-scene investigation shows," the authors conclude.

Alkaline Soil Sample From Mars Reveals Presence of Nutrients for Plants to Grow

Stick an asparagus plant in a pot full of Martian soil, and the asparagus might grow happily, scientists announced Thursday.An experiment on the Phoenix Mars lander showed the dirt on the planet’s northern arctic plains to be alkaline, though not strongly alkaline, and full of the mineral nutrients that a plant would need. “We basically have found what appears to be the requirements, the nutrients, to support life whether past, present or future,” said Samuel P. Kounaves of Tufts University, who is leading the chemical analysis, during a telephone news conference on Thursday. “The sort of soil you have there is the type of soil you’d probably have in your backyard.” Mars today is cold and dry, and the surface is bombarded by ultraviolet radiation, making life unlikely, but conditions could have made the planet more habitable in the past. Plants that like alkaline soil — like asparagus — might readily grow in the Martian soil, provided that other components of an Earth-like environment including air and water were also present.

Silicon Photonic Crystals Key To Invisibility

Now you see it, soon you might not, reearchers at the University of Illinois say. In computer simulations, the researchers have demonstrated an approximate cloaking effect created by concentric rings of silicon photonic crystals. The mathematical proof brings scientists a step closer to a practical solution for optical cloaking. In October 2006, an invisibility cloak operating in the microwave region of the electromagnetic spectrum was reported by researchers at Duke University, Imperial College in London, and Sensor Metrix in San Diego. In their experimental demonstration, microwave cloaking was achieved through a thin coating containing an array of tiny metallic structures called ring resonators.To perform the same feat at much smaller wavelengths in the visible portion of the spectrum, however, would require ring resonators smaller than can be made with current technology, Johnson said. In addition, because metallic particles would absorb some of the incident light, the cloaking effect would be incomplete. Faintly outlined in the shape of the container, some of the background objects would appear dimmer than the rest.To avoid these problems, postdoctoral research associate Dong Xiao came up with the idea of using a coating of concentric rings of silicon photonic crystals. The width and spacing of the rings can be tailored for specific wavelengths of light."When light of the correct wavelength strikes the coating, the light bends around the container and continues on its way, like water flowing around a rock," Xiao said. "An observer sees what is behind the container, as though it isn't there. Both the container and its contents are invisible." Currently simulated in two dimensions, the cloaking concept could be extended to three dimensions, Xiao said, by replacing the concentric rings with spherical shells of silicon, separated by air or some other dielectric.The researchers' optical cloaking technique is not perfect, however. "The wave fronts are slightly perturbed as they pass around the container," said Johnson, who also is affiliated with the university's Beckman Institute and the Frederick Seitz Materials Research Laboratory. "Because the wave fronts don't match exactly, we refer to the technique as 'approximate' cloaking."

Building Giant 'Nanoassemblies' That Sense Their Environment

Researchers in Texas are reporting the design, construction, and assembly of nano-size building blocks into the first giant structures that can sense and respond to changes in environmental conditions.The researchers describe development of a hybrid nanowire consisting of segments with water-repelling carbon nanotubes on one end and water-attracting metal nanowires on the other end. In laboratory tests, they showed that the nanowires could assemble themselves into larger, more complex structures when placed in water. The structures also sensed and responded to their environment by making movements when exposed to chemicals, magnets, and light.The findings "could lead to the creation of smart materials that are a cornerstone for the development of nanotechnology-based applications," the study notes.

Women Have Not Adapted To Casual Sex, Research Shows

The sexual and feminist revolutions were supposed to free women to enjoy casual sex just as men always had. Yet according to Professor Anne Campbell from Durham University in the UK, the negative feelings reported by women after one-night stands suggest that they are not well adapted to fleeting sexual encounters. Men are more likely to reproduce and therefore to benefit from numerous short-term partners. For women, however, quality seems to be more important than quantity. Also for women, finding partners of high genetic quality is a stronger motivator than sheer number, and it is commonly believed that women are more willing to have casual sex when there is a chance of forming a long-term relationship.

Neuroscientists Discover A Sense Of Adventure

Wellcome Trust scientists have identified a key region of the brain which encourages us to be adventurous. The region, located in a primitive area of the brain, is activated when we choose unfamiliar options, suggesting an evolutionary advantage for sampling the unknown. It may also explain why re-branding of familiar products encourages to pick them off the supermarket shelves.Using fMRI scanners, which measure blood flow in the brain to highlight which areas are most active, Dr Bianca Wittmann and colleagues showed that when the subjects selected an unfamiliar option, an area of the brain known as the ventral striatum lit up, indicating that it was more active. The ventral striatum is in one of the evolutionarily primitive regions of the brain, suggesting that the process can be advantageous and will be shared by many animals. "Seeking new and unfamiliar experiences is a fundamental behavioural tendency in humans and animals," says Dr Wittmann. "It makes sense to try new options as they may prove advantageous in the long run. For example, a monkey who chooses to deviate from its diet of bananas, even if this involves moving to an unfamiliar part of the forest and eating a new type of food, may find its diet enriched and more nutritious."When we make a particular choice or carry out a particular action which turns out to be beneficial, it is rewarded by a release of neurotransmitters such as dopamine. These rewards help us learn which behaviours are preferable and advantageous and worth repeating. The ventral striatum is one of the key areas involved in processing rewards in the brain. Although the researchers cannot say definitively from the fMRI scans how novelty seeking is being rewarded, Dr Wittmann believes it is likely to be through dopamine release. However, whilst rewarding the brain for making novel choices may prove advantageous in encouraging us to make potentially beneficial choices, it may also make us more susceptible to exploitation. "The novelty bonus may be useful in helping us make complex, uncertain decisions, but it clearly has a downside," says Professor Daw. "In humans, increased novelty-seeking may play a role in gambling and drug addiction, both of which are mediated by malfunctions in dopamine release."

'Feeling Fat' Is Worse Than Being It, German Study Finds

The quality of life of adolescents who think they are too fat is worse than for adolescents who really are obese. This was a result of the all Germany Health Interview and Examination Survey for Children and Adolescents (KiGGS) of the Robert Koch Institute, as presented by Bärbel-Maria Kurth and Ute Ellert in the current edition of Deutsches Ärzteblatt International.In the course of the KiGGS study, almost 7000 boys and girls aged between 11 and 17 years were weighed and asked about their self-assessment, ranging from "far too thin" to "far too fat." In addition, they all completed a questionnaire about quality of life. As a result of their analysis, the scientists established that about three quarters of adolescents are of normal weight. Almost 55% of the girls, but just under 36% of the boys thought that they were "too fat," although only about 18% of the adolescents were actually overweight. 7% to 8% of the adolescents were underweight.The quality of life is lower in obese adolescents. However, this correlates to a large extent with self-evaluation. If adolescents think they are "far too fat," they forfeit a lot of their quality of life, whatever their actual weight. This is particularly marked with girls. On the other hand, if they consider their weight "just right," their quality of life is the same as if they were of normal weight, even if this is not true. The proportion of adolescents who think they are overweight has been increasing more rapidly in recent years than the proportion of those who really are overweight.In an accompanying editorial, Johannes Hebebrand points out that adolescents are exposed to considerable social pressure to be thin. He thinks that it is remarkable that as many as 40% of the subjects thought that their weight was right, in spite of the ideal of slimness and the stigma of being overweight. -sciencedaily

Tissue Regeneration: New Source Of Heart Stem Cells Discovered

Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells. These stem cells, located in the surface of the heart, or epicardium, advance the hope of being able to regenerate injured heart tissue."There's a lot of interest in finding places to obtain new cardiomyocytes, because in heart failure, you lose cardiomyocytes, so the only way to reverse heart failure is to make more of these cells," said William Pu, MD, a pediatric cardiologist at Children's who was the study's senior investigator. -science daily

Phoenix Mars Lander Confirms Frozen Water On Red Planet

Scientists relishing confirmation of water ice near the surface beside NASA's Phoenix Mars Lander anticipate even bigger discoveries from the robotic mission in the weeks ahead."It is with great pride and a lot of joy that I announce today that we have found proof that this hard bright material is really water ice and not some other substance," said Phoenix Principal Investigator Peter Smith of the University of Arizona, Tucson, during a Friday news briefing to announce the confirmation of water ice."The truth we're looking for is not just looking at ice. It is in finding out the minerals, chemicals and hopefully the organic materials associated with these discoveries," said Smith. sciencedaily-

A Green Coal Baron?

When I met with Jim Rogers one day this spring, he tossed back two double espressos in a single hour. A charming and natty 60-year-old, Rogers is the chief executive of the electric company Duke Energy. But he has none of the macho, cowboy stolidity you might expect in an energy C.E.O. Instead, he lives to brainstorm. He spends more than half his time on the road, a perennial fixture at wonky gatherings like the Davos World Economic Forum and the Clinton Global Initiative, corralling “clean energy” thinkers and listening eagerly to their ideas. The day we met, he was brimming with enthusiasm for a new approach to solar power. Solar is currently too expensive to make economic sense, according to Rogers, because the cost to put panels on a roof is greater than what a household would save on electricity. But what if Duke bought panels en masse, driving the price down, and installed them itself — free?“So we have 500,000 solar units on the roofs of our customers,” he said. “We install them, we maintain them and we dispatch them, just like it was a power plant!” He did some quick math: he could get maybe 1,000 megawatts out of that system, enough to permanently shutter one of the company’s older power plants. He shot me a toothy grin.

Even in this era of green evangelism, Rogers is a genuine anomaly. As the head of Duke Energy, with its dozens of coal-burning electric plants scattered around the Midwest and the Carolinas, he represents one of the country’s biggest sources of greenhouse gases. The company pumps 100 million tons of carbon dioxide into the atmosphere each year, making it the third-largest corporate emitter in the United States.
Yet Rogers, who makes $10 million a year, is also one of the electricity industry’s most vocal environmentalists. For years, he has opened his doors to the kinds of green activists who would give palpitations to most energy C.E.O.’s. In March, he had breakfast with James Lovelock, the originator of the Gaia theory, which regards the earth as a single, living organism, to discuss whether species can adapt to a warmer earth. In April, James Hansen, a climatologist at NASA and one of the first scientists to publicly warn about global warming, wrote an open letter urging Rogers to stop burning coal — so Rogers took him out for a three-hour dinner in Manhattan. “I would dare say that no one in the industry would talk to Lovelock and Hansen,” Rogers told me. Last year, Rogers astonished his board when he presented his plan to “decarbonize” Duke Energy by 2050 — in effect, to retool the utility so that it emits very little carbon dioxide.
Perhaps most controversial, though, Rogers has long advocated stiff regulation of greenhouses gases. For the last few years, he has relentlessly lobbied Washington to create a “carbon cap” law that strictly limits the amount of carbon dioxide produced in the United States, one that would impose enormous costs on any company that releases more carbon than its assigned limit. That law is now on its way to becoming reality: last fall, Senators Joe Lieberman and John Warner introduced a historic “cap-and-trade” bill that would require the country to reduce its co2 emissions by 70 percent before 2050. Earlier this month, the bill failed to advance, but its sponsors will most likely reintroduce it next year once a new president is in office; meanwhile, a half-dozen other rival bills are currently being drawn up that all seek the same thing. One way or another, a carbon cap is coming. NYTimes-

Two Supermassive Black Holes Spiraling Toward Collision

A pair of supermassive black holes in the distant universe are intertwined and spiraling toward a merger that will create a single super-supermassive black hole capable of swallowing billions of stars, according to a new study by astronomers at the University of Virginia, Bonn University and the U.S. Naval Research Laboratory. Black holes are among the oldest regions of the universe and hold clues to understanding the formation of the universe and its destiny. Though astronomers have theorized that coupled black holes exist, and that black holes sometimes merge and form supermassive black holes, the new study provides further evidence that this in fact occurs."The two key questions about supermassive black holes are: Where do they come from and how do they grow over time?" said Craig Sarazin, the W.H. Vanderbilt Professor of Astronomy at the University of Virginia and co-author of the study. "The birth, care and nurturing of supermassive black holes is a very active area of study in astronomy."Supermassive black holes are areas in space that are so dense and massive they contain up to billions of stars and continually suck in more stars, further building their mass and gravitational pull. Even light cannot escape the pull of gravity in a black hole. The area appears as it is described: a black hole in space."Black holes are the ultimate garbage disposals," Sarazin said. "The material they swallow disappears without any trace, except for the gravity of the black hole." "There is no way to determine how a black hole was created or what kinds of things it has swallowed just by looking at the resulting black hole," Sarazin said. "You have to catch the black hole when it is sitting down to dinner or still eating." That, essentially, is what the Sarazin team has accomplished. They focused their observations on the center of a cluster of galaxies named Abell 400 where astronomers had previously suggested that a pair of supermassive black holes might be colliding. The two holes seemed to be relatively close together, but there was no proof that they were bound to one another or merging."The question was: Is this pair of supermassive black holes an old married couple, or just strangers passing in the night?" Sarazin said. "We now know that they are coupled, but more like the mating of black widow spiders. One of the black holes invariably will eat the other."

Astronomers Find Evidence For Tens Of Thousands Of Black Holes in our galaxy

UCLA astronomers present the first evidence that tens of thousands of black holes are orbiting the monstrous black hole at the center of the Milky Way, 26,000 light years away.Michael Muno, a UCLA postdoctoral Hubble Fellow, has studied the inner 75 light-years of the Milky Way, searching for bright, highly variable X-ray sources likely to be accreting black holes and neutron stars, using NASA's Chandra X-ray Observatory. Muno found that these "transient" X-ray sources were highly concentrated within three light-years of the Galactic center, and that the one closest to the center, only three-tenths of a light year away, was very likely to be a black hole. The best explanation for this high concentration of X-ray binaries is that a few of the black holes, which UCLA astronomy professor Mark Morris predicted in 1993 should be there, have captured other stars, and are slowly devouring them. Morris proposed a theory that a process called dynamical friction would cause stellar black holes to sink toward the center of the galaxy. The supermassive black hole, with a mass more than 3 million times that of our sun, is in the constellation of Sagittarius. Black holes are collapsed stars so dense that nothing can escape their gravitational pull, not even light. Black holes cannot be seen directly, but their influence on nearby stars is visible, and provides a signature. The black hole at the center of our galaxy came into existence billions of years ago, perhaps as very massive stars collapsed at the end of their life cycles and coalesced into a single, supermassive object.

New Panorama Reveals More Than A Thousand supermassive Black Holes

By casting a wide net, astronomers have captured an image of more than a thousand supermassive black holes. These results give astronomers a snapshot of a crucial period when these monster black holes are growing, and provide insight into the environments in which they occur.The new black hole panorama was made with data from NASA's Chandra X-ray Observatory, the Spitzer Space Telescope and ground-based optical telescopes. The black holes in the image are hundreds of millions to several billion times more massive than the sun and lie in the centers of galaxies.Material falling into these black holes at high rates generates huge amounts of light that can be detected in different wavelengths. These systems are known as active galactic nuclei, or AGN."We're trying to get a complete census across the universe of black holes and their habits," said Ryan Hickox of the Harvard-Smithsonian Center for Astrophysics (CfA) in Cambridge, Mass. "We used special tactics to hunt down the very biggest black holes."

NASA's Chandra Finds Black Holes Are 'Green'

Black holes are the most fuel efficient engines in the Universe, according to a new study using NASA's Chandra X-ray Observatory. By making the first direct estimate of how efficient or "green" black holes are, this work gives insight into how black holes generate energy and affect their environment.he new Chandra finding shows that most of the energy released by matter falling toward a supermassive black hole is in the form of high-energy jets traveling at near the speed of light away from the black hole. This is an important step in understanding how such jets can be launched from magnetized disks of gas near the event horizon of a black hole."Just as with cars, it's critical to know the fuel efficiency of black holes," said lead author Steve Allen of the Kavli Institute for Particle Astrophysics and Cosmology at Stanford University, and the Stanford Linear Accelerator Center. "Without this information, we cannot figure out what is going on under the hood, so to speak, or what the engine can do."Allen and his team used Chandra to study nine supermassive black holes at the centers of elliptical galaxies. These black holes are relatively old and generate much less radiation than quasars, rapidly growing supermassive black holes seen in the early Universe. The surprise came when the Chandra results showed that these "quiet" black holes are all producing much more energy in jets of high-energy particles than in visible light or X-rays. These jets create huge bubbles, or cavities, in the hot gas in the galaxies.The efficiency of the black hole energy-production was calculated in two steps: first Chandra images of the inner regions of the galaxies were used to estimate how much fuel is available for the black hole; then Chandra images were used to estimate the power required to produce the cavities."If a car was as fuel-efficient as these black holes, it could theoretically travel over a billion miles on a gallon of gas," said coauthor Christopher Reynolds of the University of Maryland, College Park.New details are given about how black hole engines achieve this extreme efficiency. Some of the gas first attracted to the black holes may be blown away by the energetic activity before it gets too near the black hole, but a significant fraction must eventually approach the event horizon where it is used with high efficiency to power the jets. The study also implies that matter flows towards the black holes at a steady rate for several million years."These black holes are very efficient, but it also takes a very long time to refuel them," said Steve Allen who receives funding from the Office of Science of the Department of Energy.This new study shows that black holes are green in another important way. The energy transferred to the hot gas by the jets should keep hot gas from cooling, thereby preventing billions of new stars from forming. This will place limits on the growth of the largest galaxies, and prevent galactic sprawl from taking over the neighborhood. sciencedaily-

Memory Loss Linked To Poor Diet

Loss of memory with advanced age is a significant problem within most societies, and appears particularly severe in advanced industrialized nations. A less visible and often ignored problem comes from a food supply high in cholesterol and saturated fat, which has led to high obesity rates particularly in the United States.Researchers from the Medical University of South Carolina (MUSC) have linked memory loss to a diet high in saturated fat and cholesterol.Collaboration between two laboratories at MUSC and one at Arizona State University led researchers to discover that rodents that were fed a diet high in cholesterol and saturated fat displayed impairment in working memory. This memory loss is associated with inflammation in the brain, as well as the impairment of structural proteins that affect how a nerve cell functions. As inflammation is associated with a poor diet, the failure of functions in other key organs such as the eye and the ear also could be expected. Assuming that the same phenomenon occurs in human beings, the study suggests that as humans age, memory may be preserved and brain functions improved by restricting the consumption of cholesterol and saturated fats. As cases of obesity and obesity-related diseases have increased exponentially in the United States, and are second only to tobacco use for premature mortality and the number of health-care dollars spent, the importance of this issue is immediate. -science daily

Depression And Diabetes: Fellow Travelers, Researchers Say

Researchers have long known that type-2 diabetes and depression often go hand in hand. However, it's been unclear which condition develops first in patients who end up with both. Now, a new study led by Johns Hopkins doctors suggests that this chicken-and-egg problem has a dual answer: Patients with depression have an increased risk of developing type-2 diabetes, and patients with type-2 diabetes have an increased risk of developing depression.Results showed that those with elevated depressive symptoms were 42 percent more likely overall to develop diabetes by the end of the study than those without these symptoms. Moreover, the stronger the symptoms, the higher the risk of diabetes, a "dose response" that lends strength to the findings.Even when the researchers accounted for such factors as overweight, lack of exercise, and smoking, the risk of developing diabetes was still 34 percent higher for patients with depressive symptoms. To investigate whether diabetes could lead to depression, Golden and her colleagues used the same pool of MESA information and excluded those who had elevated depressive symptoms at the initial clinic visit. Then, they looked to see whether those who had high fasting glucose--with or without a formal diagnosis of diabetes--were more likely to develop depressive symptoms by the end of the study.The researchers found that patients treated for diabetes, about 9 percent of the group, were about 54 percent more likely to develop elevated depressive symptoms than those without diabetes.Surprisingly, those with prediabetes or untreated diabetes were about 25 percent less likely to develop elevated depressive symptoms than people with normal fasting glucose, a finding Golden's team cannot explain at this time."It's important that doctors be attuned to look for both conditions in patients at risk for either diabetes or depression," Golden adds. "We may want to develop interventions for both treatments, instead of just one or the other." -sciencedaily

Elderly's Restless Nights Helped By Ancient Martial Art

More than half of all older adults complain about having difficulties sleeping. Most don't bother seeking treatment. Those who do usually turn either to medications, which can lead to other health problems, or behavior therapies, which are costly and often not available close to home.Now, UCLA researchers report that practicing tai chi chih, the Westernized version of a 2,000-year-old Chinese martial art, promotes sleep quality in older adults with moderate sleep complaints. The study, which will be published in the journal Sleep, is currently available in the journal's online edition.In the study, 112 healthy adults ranging in age from 59 to 86 were randomly assigned to one of two groups for a 25-week period: The first group practiced 20 simple tai chi chih moves; the other participated in health education classes that included advice on stress management, diet and sleep habits.At the beginning of the study, participants were asked to rate their sleep based on the Pittsburgh Sleep Quality Index, a self-rated questionnaire that assesses sleep quality, duration and disturbances over a one-month time interval.The study found that the tai chi chih group showed improved sleep quality and a remission of clinical impairments, such as drowsiness during the day and inability to concentrate, compared with those receiving health education. The tai chi chih participants showed improvements in their own self-rating of sleep quality, sleep duration and sleep disturbance.And while most health professionals generally agree that physical exercise enhances sleep quality, given the physical limitations of the elderly, rigorous exercise might not be an option. That's why tai chi chih, with its gentle, slow movements, is an attractive exercise option for the elderly population."It's a form of exercise virtually every elderly person can do, and this study provides more across-the-board evidence of its health benefits," Irwin said. -sciencedaily

Surprisingly Rapid Changes In Earth’s Core Discovered

The movements in the liquid part of the Earth’s core are changing surprisingly quickly, and this affects the Earth’s magnetic field, according to new research from DTU Space.The Ørsted satellite’s very precise measurements of the Earth’s magnetic field over the past nine years have made it possible for Nils Olsen, Senior Scientist with DTU Space, and several German scientists, to map surprisingly rapid changes in the movements in the Earth’s core. The results have just been published in the scientific journal Nature Geoscience.“What is so surprising is that rapid, almost sudden, changes take place in the Earth’s magnetic field. This suggests that similar sudden changes take place in the movement of the liquid metal deep inside the Earth which is the reason for the Earth’s magnetic field,” Nils Olsen explains.The Earth’s core consists of an inner solid core which is surrounded by an outer liquid core approx. 3,000 km below our feet. Both the liquid core and the solid core consist primarily of iron and nickel, and it is the movements in the outer liquid part of the Earth’s core which create the Earth’s magnetic field. Changes in these movements are seen as changes in the magnetic field, and scientists can therefore use satellite measurements of the magnetic field to find out what is going on in the liquid core deep inside the Earth.Scientists from DTU Space and other institutions are currently preparing a joint European successor to the Ørsted satellite by the name of Swarm. The Swarm mission consists of three satellites, which will be measuring the Earth’s magnetic field even more accurately than the Ørsted satellite.“By combining the Swarm and Ørsted magnetic measurements we hope to find out the reason for the-se rapid movements in the core,” Nils Olsen concludes. -sciencedaily

Zebra's Stripes, Butterfly's Wings: How Do Biological Patterns Emerge?

A zebra’s stripes, a seashell’s spirals, a butterfly’s wings: these are all examples of patterns in nature. The formation of patterns is a puzzle for mathematicians and biologists alike. How does the delicate design of a butterfly’s wings come from a single fertilized egg? How does pattern emerge out of no pattern?Using computer models and live cells, researchers at Johns Hopkins have discovered a specific pattern that can direct cell movement and may help us understand how metastatic cancer cells move.“Pattern formation is a classic problem in embryology,” says Denise Montell, Ph.D., a professor of biological chemistry at Hopkins. “At some point, cells in an embryo must separate into those that will become heart cells, liver cells, blood cells and so on. Although this has been studied for years, there is still a lot we don’t understand.” _science Daily